Rabbit sera block binding of mAbs to gp120.
- Kristin M. Narayan (105322)
- Nitish Agrawal (105325)
- Sean X. Du (105326)
- Janelle E. Muranaka (105327)
- Katherine Bauer (105328)
- Daniel P. Leaman (105329)
- Pham Phung (105330)
- Kay Limoli (105331)
- Helen Chen (105332)
- Rebecca I. Boenig (105333)
- Terri Wrin (105334)
- Michael B. Zwick (105335)
- Robert G. Whalen (105336)
Publication date
January 2013
DOIAbstract
<p>Competition ELISA using various mAbs and sera to block binding of biotinylated (bio) 2G12 (A, C) and b12 (B, D) to immobilized JR-CSF gp120. Two normal rabbit sera are used as non-immune controls. The results shown are representative of three independent experiments. The dashed horizontal line (—) corresponds to the half-maximal signal (EC50). HIVIG: HIV immune globulin provided by J. Mascola (VRC); DEN3: a mAb to dengue virus envelope provided by D. Burton (TSRI).</p
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