<p><b>A</b>) Expression values obtained in the microarray analysis for some genes involved in cell cycle arrest at G1 or G2. SM and HE refer to each of the gene expression analyses made, in skeletal muscle and in heart. <i>n.s.</i> indicates that the gene is not significantly up- or down-regulated in the analysis. <b>B</b>) Expression of <i>Cdkn1a</i> (p21) was also analysed by Real-time qPCR for both tissues. The <i>P</i>-values for statistical comparisons (two-tailed unpaired Student's t-test) between <i>Tk2</i><sup>+/+</sup> and <i>Tk2</i><sup>−/−</sup> tissues are shown - *<i>P</i><0.05; **<i>P</i><0.01.</p
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>qRT-PCR was performed on mRNA isolated from quadriceps muscle of <i>Cfl2</i> KO mice and compared...
<p>(A) Tissue-specific expression of <i>Ak2</i>, <i>Ckmt1</i>, <i>Ckmt2</i>, and <i>Ndpk-d</i> mRNA ...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p>RT-qPCR revealed altered transcription of some cardiac genes examined such as BNP and myosin ligh...
<p>Data are expressed as mean fold change in TK2<sup>−/−</sup> samples relative to TK2<sup>+/+</sup>...
Objective: To study postnatal cardiac differentiation in the mouse. Hypothesis: There might be mecha...
Cellular differentiation is accompanied by the modulation of gene expression. I have compared the ex...
<p>mRNA expression of tRNA splicing endonuclease 3 (Tsen15; <b>panel a</b>), Growth arrest specific ...
<p>(<b>A</b>) Schematic of microarray loop experiment. RNA isolated from G<sub>0</sub> MB was analyz...
The Cdkn2a locus is one of the most studied tumor suppressor loci in the context of several cancer t...
<p><b>(A)</b> Diagram indicating the total number of differentially expressed genes (TG vs NT) ident...
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>qRT-PCR was performed on mRNA isolated from quadriceps muscle of <i>Cfl2</i> KO mice and compared...
<p>(A) Tissue-specific expression of <i>Ak2</i>, <i>Ckmt1</i>, <i>Ckmt2</i>, and <i>Ndpk-d</i> mRNA ...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p>RT-qPCR revealed altered transcription of some cardiac genes examined such as BNP and myosin ligh...
<p>Data are expressed as mean fold change in TK2<sup>−/−</sup> samples relative to TK2<sup>+/+</sup>...
Objective: To study postnatal cardiac differentiation in the mouse. Hypothesis: There might be mecha...
Cellular differentiation is accompanied by the modulation of gene expression. I have compared the ex...
<p>mRNA expression of tRNA splicing endonuclease 3 (Tsen15; <b>panel a</b>), Growth arrest specific ...
<p>(<b>A</b>) Schematic of microarray loop experiment. RNA isolated from G<sub>0</sub> MB was analyz...
The Cdkn2a locus is one of the most studied tumor suppressor loci in the context of several cancer t...
<p><b>(A)</b> Diagram indicating the total number of differentially expressed genes (TG vs NT) ident...
<p>(A) Heart weight (HW) normalized to body weight (BW) in tTA and NLK DTG mice at the indicated age...
<p>qRT-PCR was performed on mRNA isolated from quadriceps muscle of <i>Cfl2</i> KO mice and compared...
<p>(A) Tissue-specific expression of <i>Ak2</i>, <i>Ckmt1</i>, <i>Ckmt2</i>, and <i>Ndpk-d</i> mRNA ...