<p>For each time point, data from at least 3 different mice have been used (<i>n</i>≥3). The <i>P</i>-values for statistical comparisons (two-tailed unpaired Student's t-test) between <i>Tk2</i><sup>+/+</sup> and <i>Tk2</i><sup>−/−</sup> tissues are shown - *<i>P</i><0.05;</p>**<p><i>P</i><0.01.</p
<p>Total DNA was prepared from the hearts of a 10-month-old wild-type mouse (WT) and an age matched ...
<p>Representative autoradiograms from Southern blot analyses of (A) mtDNA and (B) nDNA are shown for...
(A) Quantification of mtDNA residual levels in mouse reconstructed blastocysts (karyoplast and cytop...
<p>Bars depict mtDNA copy number per cell from mice aged four months. Tissues analyzed included brai...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p>(A-F) Satellite cells from uninjured muscle or activated by injury for different times were isola...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p>For each measurement, data from at least 3 different mice have been used (<i>n</i>≥3).The <i>P</i...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p>A representative profile of mtDNA heteroplasmy levels in hematopoietic (spleen, peripheral blood,...
The changes in telomere length and mitochondrial DNA copy number (mtDNAcn) are considered to be agin...
<p>MtDNA copy number relative to nuclear DNA was measured in the spleen of three month F2 (BALB/c X ...
<p>(A). The pattern of rDNA copy number from 15 different tissues from C57BL/6 mice, (B). The patter...
<p>Body weight (A) and daily food consumption (B) in mtDNA mutator (mut) mice in comparison to litte...
<p>Total DNA was prepared from the hearts of a 10-month-old wild-type mouse (WT) and an age matched ...
<p>Representative autoradiograms from Southern blot analyses of (A) mtDNA and (B) nDNA are shown for...
(A) Quantification of mtDNA residual levels in mouse reconstructed blastocysts (karyoplast and cytop...
<p>Bars depict mtDNA copy number per cell from mice aged four months. Tissues analyzed included brai...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p>(A-F) Satellite cells from uninjured muscle or activated by injury for different times were isola...
Loss of thymidine kinase 2 (TK2) causes a heterogeneous myopathic form of mitochondrial DNA (mtDNA) ...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p>For each measurement, data from at least 3 different mice have been used (<i>n</i>≥3).The <i>P</i...
<p><b>A</b>) Gene variation obtained by microarray analysis. SM and HE refer to each of the gene exp...
<p>A representative profile of mtDNA heteroplasmy levels in hematopoietic (spleen, peripheral blood,...
The changes in telomere length and mitochondrial DNA copy number (mtDNAcn) are considered to be agin...
<p>MtDNA copy number relative to nuclear DNA was measured in the spleen of three month F2 (BALB/c X ...
<p>(A). The pattern of rDNA copy number from 15 different tissues from C57BL/6 mice, (B). The patter...
<p>Body weight (A) and daily food consumption (B) in mtDNA mutator (mut) mice in comparison to litte...
<p>Total DNA was prepared from the hearts of a 10-month-old wild-type mouse (WT) and an age matched ...
<p>Representative autoradiograms from Southern blot analyses of (A) mtDNA and (B) nDNA are shown for...
(A) Quantification of mtDNA residual levels in mouse reconstructed blastocysts (karyoplast and cytop...