Connectivity associated with left PCUN seed and connectivity reductions in CN, MCI, and AD. A.

<p>Correlation coefficients map (R-map) showing connectivity associated with left PCUN seed in CN. <b>B.</b> R-map showing connectivity associated with left PCUN seed in MCI. <b>C.</b> R-map showing connectivity associated with left PCUN seed in AD. <b>D.</b> Z-statistics map showing reduced connectivity with left PCUN seed in MCI compared to CN. <b>E.</b> Z-statistics map showing reduced connectivity left PCUN seed in AD compared to CN (<i>p</i><0.05, FDR-corrected). PCUN = precuneus; CN = cognitively normal; MCI = mild cognitive impairment; AD = Alzheimer’s disease; L = left; R = right.