Overview of DNA hypermethylation status for 12 miRNA promoters analyzed by MassARRAY.

<p>miRNA genes are listed on the left, sample names are on the top. miRNA promoters that have significant ≥20% increase in DNA methylation within the whole MassARRAY amplicon relative to normal samples are in black. For a select set of miRNAs, 14 additional breast cancer specimens were analyzed. Cancer cell lines and tumor tissue samples are separated by vertical grey line. The mir-31 promoter of MB231 sample is grey because this cell line has a homozygous deletion of this region.