GW3965 augments ABCA1 levels in WT and apoE−/− mice following mrTBI.

<p>ABCA1 protein levels were determined in ipsilateral half brains of WT (<b>A</b>) and apoE−/− (<b>B</b>) mice following mrTBI using Western blots, with representative blots shown below the graphs. Data are expressed as fold difference normalized to sham values. Data from sham animals within each genotype were pooled (grey bars). Numbers inside the bars indicate sample size. Asterisks above individual bars indicate significant difference compared to the respective sham levels. *: <i>p</i><0.05, **: <i>p</i><0.01, ***: <i>p</i><0.001, ****: <i>p</i><0.0001. Data were analyzed by two-way ANOVA followed by a Bonferroni post hoc test. Legend: S: sham V: untreated mice, open bars, G: GW3965-treated mice, black bars.