<i>T. spiralis</i> induced enteritis and peripheral myositis produces a CCK dependent and independent bi-phasic hypophagia.

<p>Food intake of naïve and infected wild-type (<i>A</i>) and CCK^lacZ (<i>B</i>) mice, derived via weighing chow daily. Representative CCK (<i>C</i>) and lacZ (<i>D</i>) I-cell staining from day 9 p.i. wild-type and CCK^lacZ duodenum respectively. Black arrows indicate I-cells. Black bar = 100 µm. (<i>E</i>) Number of CCK/LacZ positive I-cells/20 VCU in wild-type and CCK^lacZ mice as determined from immunohistochemistry or immunofluorescence respectively. Data (n = 8–10 mice/group) from two independent experiments. *, P<0.05; **, P<0.01; or ***, P<0.005 between naïve and infected groups, error bars represent SE of means.