Analysis of <i>IRF5</i> transcripts containing the Ex6 in/del.

<p>Using estimated transcript read counts obtained from MMSeq, expression of transcripts containing vs. those missing the Ex6c deletion was compared in healthy donors (n = 4) and SLE patients carrying the H2 risk haplotype (n = 4). Shown are the total number of reads aligned per group of patients. ^aχ² = 1377726 with <i>p</i><2.2×10⁻¹⁶; <i>p</i> values were obtained by the Pearson’s χ²-test with Yates continuity correction. Totaled reads mapping to the Ex6C deletion were similarly compared across grouped healthy vs. SLE (risk) patients; ^bχ² = 16.0379 with <i>p</i><6.209×10⁻¹⁵. Σ = sum.