Effects of synthetic indole on <i>C. elegans</i>.

<p>(<b>a</b>) Effects on survival of <i>C. elegans</i> N2 upon exposure to various concentrations of synthetic indole in LB broth for 3 hours. (<b>b</b>) Effects on survival of <i>C. elegans</i> N2 and various mutants upon exposure to 3.5 mM synthetic indole in LB broth for 3 hours. In a-b, mean +/− SEM are shown; * corresponds to p<0.01 with respect to controls (1.5 mM in A; N2 in b). (<b>c</b>) Effects of pre-exposure of N2 or various mutants to 3.5 mM indole for 15 minutes followed by a 3 hour waiting period on OP50, and then a 3 hour challenge with 3.5 mM indole. The grey bar indicates the percent survival without conditioning. (<b>d,e</b>) Effects of pre-exposure of N2 or <i>daf-16(mgDF47)</i> to indole (15 minutes) or to EPEC (30 minutes) followed by a 3 hour waiting period on OP50, and then a 3 hour challenge with either EPEC/LBT (<b>d</b>) or 3.5 mM indole (<b>e</b>). In both cases, only N2 was conditionable. In c-e, mean +/−95% confidence intervals are shown. Lack of overlapping error bars indicates significance at the 5% level.