Summary of the observed baseline regulation in renal cortices with various MK2 and MK3 genotypes.

1<p>The negative effect of MK3 on MNK1 expression was inhibited by MK2.</p><p>MK2 and/or MK3 altered expression of HSPB8, CHOP, and MNK1, and phosphorylation of eIF2α, MK5, and MSK1, in the indicated manner. Positive (↑) and negative (↓) effects of MK2 and/or MK3 on expression or phosphorylation of various stress indicator proteins and MKs are indicated by the corresponding arrows, and weak responses are indicated by parentheses. Responses that apparently depended on the action of MK2 or MK3 alone are indicated in columns I and II, respectively. Responses that seemed to involve both MK2 and MK3, are indicated in column III.