<p><b>A.</b> BMMs from NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>) mice were infected with indicated bacteria for one hour, and then immunostained with FITC-labeled anti-ASC antibody (green) and Cy5-labeled anti-<i>V. parahaemolyticus</i> antibody (red). The merged images were shown. Bar, 10 µm. <b>B.</b> Quantitative data of number of speck-forming macrophages in <b>A</b>. Data are presented as the means ± SD of triplicate samples. *p<0.05.</p
(A-P) Immunofluorescence microscopy-based detection of F4/80-positive macrophages in renal or liver ...
<p>C57BL/6 and <i>Nlrp3<sup>−/−</sup></i> mice were infected intranasally with <i>A. fumigatus</i> a...
WT and KO (N = 6-8/group/time point) mice were infected with a sublethal dose of S. aureus (5 X 107 ...
<p><b>A.</b> BMMs from wild-type or NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>) mice were infected ...
<p><b>A, B and C.</b> BMMs from NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>) mice were primed with L...
<p>(A-D) Bone marrow-derived macrophages (BMDMs) from C57BL/6 (open circles), <i>Nlrc4</i><sup><i>-/...
<p>(<b>A</b>) MMP-7, ASC and NLRP-3 responses to infection were visualized by confocal microscopy. A...
(A) Lungs tissue sections from healthy controls and pneumonic patients were stained with antibodies ...
Inflammasome activation is associated with numerous diseases. However, in vivo detection of the acti...
<p>BMMs from wild-type, ASC-deficient (<i>Asc</i><sup>−/−</sup>), caspase-1-deficient (<i>Casp1</i><...
<p>BMMs were co-incubated with IgG-opsonized, labeled sheep red blood cells and phagocytic index was...
SummaryInflammasome activation is associated with numerous diseases. However, in vivo detection of t...
<p>BMDCs were derived from wild-type (WT), <i>Casp1/11<sup>−/−</sup></i> and <i>Nlrc4<sup>−/−</sup><...
<p>BMMs from wild-type, NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>), or NLRC4-deficient (<i>Nlrc4</...
<p><b>A and B.</b> Activated endogenous Cdc42 was analyzed by GST-PAK PBD pull-down and immunoblotti...
(A-P) Immunofluorescence microscopy-based detection of F4/80-positive macrophages in renal or liver ...
<p>C57BL/6 and <i>Nlrp3<sup>−/−</sup></i> mice were infected intranasally with <i>A. fumigatus</i> a...
WT and KO (N = 6-8/group/time point) mice were infected with a sublethal dose of S. aureus (5 X 107 ...
<p><b>A.</b> BMMs from wild-type or NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>) mice were infected ...
<p><b>A, B and C.</b> BMMs from NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>) mice were primed with L...
<p>(A-D) Bone marrow-derived macrophages (BMDMs) from C57BL/6 (open circles), <i>Nlrc4</i><sup><i>-/...
<p>(<b>A</b>) MMP-7, ASC and NLRP-3 responses to infection were visualized by confocal microscopy. A...
(A) Lungs tissue sections from healthy controls and pneumonic patients were stained with antibodies ...
Inflammasome activation is associated with numerous diseases. However, in vivo detection of the acti...
<p>BMMs from wild-type, ASC-deficient (<i>Asc</i><sup>−/−</sup>), caspase-1-deficient (<i>Casp1</i><...
<p>BMMs were co-incubated with IgG-opsonized, labeled sheep red blood cells and phagocytic index was...
SummaryInflammasome activation is associated with numerous diseases. However, in vivo detection of t...
<p>BMDCs were derived from wild-type (WT), <i>Casp1/11<sup>−/−</sup></i> and <i>Nlrc4<sup>−/−</sup><...
<p>BMMs from wild-type, NLRP3-deficient (<i>Nlrp3</i><sup>−/−</sup>), or NLRC4-deficient (<i>Nlrc4</...
<p><b>A and B.</b> Activated endogenous Cdc42 was analyzed by GST-PAK PBD pull-down and immunoblotti...
(A-P) Immunofluorescence microscopy-based detection of F4/80-positive macrophages in renal or liver ...
<p>C57BL/6 and <i>Nlrp3<sup>−/−</sup></i> mice were infected intranasally with <i>A. fumigatus</i> a...
WT and KO (N = 6-8/group/time point) mice were infected with a sublethal dose of S. aureus (5 X 107 ...