Genome wide expression profiling of splenocytes.

<p>(<b>A</b>) Differentially expressed 164 genes obtained from the microarray analysis were further analyzed. The area-proportional Venn diagram depicts 17 genes that were over-expressed in diabetic mice in comparison to TSA-treated mice. (<b>B</b>) Principal component analysis of diabetic/TSA-treated (F1) group indicates significant up-regulation of the same set of genes (<i>Clps, Pnlip, Cpb1, Ela3, Cpa1, Ctrb1, Ctrl, Prrs2, Rnase1, Ela1, Cel,</i> and <i>Ctrc</i>) depicted in Venn diagram (group c in <b>A</b>).