<p>MRM chromatograms comparing F-series prostaglandins in <i>C. elegans</i> and mouse tissue extracts. The F1 class was detected with mass transition <i>m/z</i> 355/311, the F2 class was detected with mass transition <i>m/z</i> 353/193, and the F3 class was detected with mass transition <i>m/z</i> 351/193. Liquid chromatography retention time (min) is shown on the X-axis and for selected prostaglandin isomers. Cps, counts per second. The <i>C. elegans</i> MRM chromatograms are from <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003271#pgen-1003271-g003" target="_blank">Figure 3A</a>. The mouse lung is extremely rich in PGE<sub>2</sub>, which was detectable with mass transition <i>m/z</i> 351/193.</p
To determine the metabolic fate of prostaglandins quantitively and qualitivcly as well, various norm...
<p>LLC-Luc cells or matrigel (control) were injected into left lung lobes of wild-type or cPLA<sub>2...
Free radical-mediated oxidation of arachidonic acid to prostanoids has been implicated in a variety ...
<p>LC-MS/MS of authentic standards (top) compared to selected <i>C. elegans</i> prostaglandins highl...
<p>Retention time (RT), parent ion mass ([M-H]<sup>−</sup>), and key product ion masses are shown. C...
<p>(A) MRM chromatograms of synchronized 1–2 day adult wild-type and <i>glp-4(bn2)</i> mutants. The ...
<p>(A) MRM chromatograms of wild-type and <i>fat</i> mutant extracts. Liquid chromatography retentio...
e50447, doi:10.3791/50447 (2013). Caenorhabditis elegans is emerging as a powerful animal model to s...
<p>(A) Endogenous PGE<sub>2</sub>, PGF<sub>2α</sub>, and 15-keto PGE<sub>2</sub> concentrations were...
<p>(A) The <i>C. elegans</i> hermaphrodite reproductive tract. A differential interference contrast ...
<p>Retention time (RT), parent ion mass ([M-H]<sup>−</sup>), and key product ion masses are shown fo...
The mechanisms that guide motile sperm through the female reproductive tract to oocytes are not well...
<div><p>The mechanisms that guide motile sperm through the female reproductive tract to oocytes are ...
The cellular origin of prostaglandins in human tumors was investigated using cell fractionation proc...
Isoprostanes are stable products of arachidonic acid peroxidation and are regarded as the most relia...
To determine the metabolic fate of prostaglandins quantitively and qualitivcly as well, various norm...
<p>LLC-Luc cells or matrigel (control) were injected into left lung lobes of wild-type or cPLA<sub>2...
Free radical-mediated oxidation of arachidonic acid to prostanoids has been implicated in a variety ...
<p>LC-MS/MS of authentic standards (top) compared to selected <i>C. elegans</i> prostaglandins highl...
<p>Retention time (RT), parent ion mass ([M-H]<sup>−</sup>), and key product ion masses are shown. C...
<p>(A) MRM chromatograms of synchronized 1–2 day adult wild-type and <i>glp-4(bn2)</i> mutants. The ...
<p>(A) MRM chromatograms of wild-type and <i>fat</i> mutant extracts. Liquid chromatography retentio...
e50447, doi:10.3791/50447 (2013). Caenorhabditis elegans is emerging as a powerful animal model to s...
<p>(A) Endogenous PGE<sub>2</sub>, PGF<sub>2α</sub>, and 15-keto PGE<sub>2</sub> concentrations were...
<p>(A) The <i>C. elegans</i> hermaphrodite reproductive tract. A differential interference contrast ...
<p>Retention time (RT), parent ion mass ([M-H]<sup>−</sup>), and key product ion masses are shown fo...
The mechanisms that guide motile sperm through the female reproductive tract to oocytes are not well...
<div><p>The mechanisms that guide motile sperm through the female reproductive tract to oocytes are ...
The cellular origin of prostaglandins in human tumors was investigated using cell fractionation proc...
Isoprostanes are stable products of arachidonic acid peroxidation and are regarded as the most relia...
To determine the metabolic fate of prostaglandins quantitively and qualitivcly as well, various norm...
<p>LLC-Luc cells or matrigel (control) were injected into left lung lobes of wild-type or cPLA<sub>2...
Free radical-mediated oxidation of arachidonic acid to prostanoids has been implicated in a variety ...