Nucleophilic Addition of Benzimidazoles to Alkynyl Bromides/Palladium-Catalyzed Intramolecular C–H Vinylation: Synthesis of Benzo[4,5]imidazo[2,1‑<i>a</i>]isoquinolines

An efficient “one-pot” route for the synthesis of benzo­[4,5]­imidazo­[2,1-<i>a</i>] isoquinolines has been developed via nucleophilic addition of 2-aryl benzimidazoles to alkynyl bromides and subsequent palladium-catalyzed intramolecular C–H vinylation