Microglia decrease the levels of synaptic adhesion molecules.

<p>Hippocampal neurons at 19 DIV were co-cultured with microglia for 2 days. <b>A.</b> Western blot analysis of the levels of N-cadherin, pan-γ-protocadherin, and SynCAM-1 in neurons in the absence or presence of microglia. α-tubulin was used as a loading control. <b>B.</b> Quantification was performed using the ImageJ software and normalized against α-tubulin (n = 4). *P<0.05 compared to neurons alone.