<p>Cells were exposed to CdCl<sub>2</sub> (5 and 10 μM) for 24 h in the absence or presence of NAC (1 mM), and then processed for (A) genomic DNA fragmentation (sub-G1 DNA content) analysis by flow cytometry, and (B) apoptotic cell observation by Annexin V-Cy3 (red fluorescence) and 6-CFDA (green fluorescence) staining (a and b, control; c and d, CdCl<sub>2</sub>-5 μM; e and f, CdCl<sub>2</sub>-10 μM; g and h, NAC-1 mM; i and j, CdCl<sub>2</sub>-5 μM + NAC; k and l, CdCl<sub>2</sub>-10 μM + NAC) as described in the Materials and Methods section. Results in A are expressed as mean ± S.D. for six independent experiments with triplicate determination after normalizing the result of cell viability. *<i>p</i><0.05 as compared with vehicle contro...
<p>(a) Representative images of cleaved caspase-3 western blot after 12-h cadmium treatment in the a...
<p>(A and B) PC12 cells were treated with 0–20 µM Cd for 24 h, or with 0, 10 and 20 µM Cd for 0–24 h...
<p>Cells were exposed to CdCl<sub>2</sub> (5 and 10 μM) for various time courses in the absence or p...
<p>(a) Representative confocal images of cadmium-induced rPT cells. (b) Quantification of calcein fl...
International audienceCell death resulting from cadmium (Cd) intoxication has been confirmed to indu...
<p>(A) After treatment of CDDP at the indicated concentrations for 24 h, genomic DNA was isolated an...
<p>SUM159 cells (<b>A</b>) and MDA-MB-231 cells (<b>B</b>) were incubated with vehicle control or CD...
<p>(A, B) NRK-52E cells were exposed to cadmium (Cd; 10 µM) in the absence or presence of rapamycin ...
<p>(A) MDBK cells were treated with 10 μM CdCl<sub>2</sub>, alone or in combination with ZnCl<sub>2<...
<p>(<b>A</b>) Control group. (<b>B</b>) 3.56-mg/L group. (<b>C</b>) 7.12-mg/L group. (<b>D</b>) 14.2...
<p>(a) Cadmium induced ROS generation dose-dependently in rPT cells. (b) Intracellular ROS levels in...
<p>(A) Cells were treated with or without CdCl<sub>2</sub> (1–10 μM) for 24 h, and cell viability wa...
PubMed ID: 14645995Cadmium is a toxic transition heavy metal of continuing occupational and environm...
<p>(A) After K562 cells were treated with 4 or 8 μM NC for 24 or 48 hrs, MTT assay was performed to ...
WOS: 000186725500005PubMed ID: 14645995Cadmium is a toxic transition heavy metal of continuing occup...
<p>(a) Representative images of cleaved caspase-3 western blot after 12-h cadmium treatment in the a...
<p>(A and B) PC12 cells were treated with 0–20 µM Cd for 24 h, or with 0, 10 and 20 µM Cd for 0–24 h...
<p>Cells were exposed to CdCl<sub>2</sub> (5 and 10 μM) for various time courses in the absence or p...
<p>(a) Representative confocal images of cadmium-induced rPT cells. (b) Quantification of calcein fl...
International audienceCell death resulting from cadmium (Cd) intoxication has been confirmed to indu...
<p>(A) After treatment of CDDP at the indicated concentrations for 24 h, genomic DNA was isolated an...
<p>SUM159 cells (<b>A</b>) and MDA-MB-231 cells (<b>B</b>) were incubated with vehicle control or CD...
<p>(A, B) NRK-52E cells were exposed to cadmium (Cd; 10 µM) in the absence or presence of rapamycin ...
<p>(A) MDBK cells were treated with 10 μM CdCl<sub>2</sub>, alone or in combination with ZnCl<sub>2<...
<p>(<b>A</b>) Control group. (<b>B</b>) 3.56-mg/L group. (<b>C</b>) 7.12-mg/L group. (<b>D</b>) 14.2...
<p>(a) Cadmium induced ROS generation dose-dependently in rPT cells. (b) Intracellular ROS levels in...
<p>(A) Cells were treated with or without CdCl<sub>2</sub> (1–10 μM) for 24 h, and cell viability wa...
PubMed ID: 14645995Cadmium is a toxic transition heavy metal of continuing occupational and environm...
<p>(A) After K562 cells were treated with 4 or 8 μM NC for 24 or 48 hrs, MTT assay was performed to ...
WOS: 000186725500005PubMed ID: 14645995Cadmium is a toxic transition heavy metal of continuing occup...
<p>(a) Representative images of cleaved caspase-3 western blot after 12-h cadmium treatment in the a...
<p>(A and B) PC12 cells were treated with 0–20 µM Cd for 24 h, or with 0, 10 and 20 µM Cd for 0–24 h...
<p>Cells were exposed to CdCl<sub>2</sub> (5 and 10 μM) for various time courses in the absence or p...