<p>Typical urine total ion current (TIC) chromatograms in positive ionization mode (A), negative ionization mode (B).</p
List of standards used, their retention times (RT) and limits of detection (LOD) is presented in S1 ...
<p>Numbers indicate the following metabolites (quantified compounds): 1: pyruvic acid; 2: L-lactic a...
<p>Typical chromatograms of free DOX (upper panel), DOX-hyd-PEG-FA (middle panel) and DOX-ami-PEG-FA...
Chromatograms of (a) blank urine, (b) urine sample spiked with 50 ppm IPA, and (c) urine sample spik...
Representative total ion chromatography (TIC) of plasma sample from sham, model and AOF groups in po...
Note: (A) blank plasma; (B) blank plasma spiked with cocktail probe drugs at LLOQ and IS; (C) sample...
<p>Examples of chromatograms (standardised resistance vs. time) of the urine of two patients with bl...
<p>Numbers indicate the following metabolites (quantified compounds): 1: L-valine; 2: oxalic acid; 3...
The plasmatic strong ion difference (SID) is the difference between positively and negatively charge...
Distribution of differential metabolites in positive ion mode (ESI+) and negative ion mode (ESI-).</...
<p>(A) NC at positive ion mode. (B) M at positive ion mode (C) <i>SHLI</i> treatment at positive mod...
Untargeted liquid chromatography–mass spectrometry (LC-MS)-based metabolomics studies are usually ca...
Total ion current base peak intensity (BPI) chromatogram in (A) positive mode and (B) negative mode....
<p>Note: Spiking concentrations were 73 nmol/L for 8OhdG and m-Tyr, 182 nmol/L for 2-dG, o-Tyr, 3NO<...
<p><b>A</b>. Receiver Operating Characteristic curve for day-0 urinary Strong Ion Difference(SIDu) t...
List of standards used, their retention times (RT) and limits of detection (LOD) is presented in S1 ...
<p>Numbers indicate the following metabolites (quantified compounds): 1: pyruvic acid; 2: L-lactic a...
<p>Typical chromatograms of free DOX (upper panel), DOX-hyd-PEG-FA (middle panel) and DOX-ami-PEG-FA...
Chromatograms of (a) blank urine, (b) urine sample spiked with 50 ppm IPA, and (c) urine sample spik...
Representative total ion chromatography (TIC) of plasma sample from sham, model and AOF groups in po...
Note: (A) blank plasma; (B) blank plasma spiked with cocktail probe drugs at LLOQ and IS; (C) sample...
<p>Examples of chromatograms (standardised resistance vs. time) of the urine of two patients with bl...
<p>Numbers indicate the following metabolites (quantified compounds): 1: L-valine; 2: oxalic acid; 3...
The plasmatic strong ion difference (SID) is the difference between positively and negatively charge...
Distribution of differential metabolites in positive ion mode (ESI+) and negative ion mode (ESI-).</...
<p>(A) NC at positive ion mode. (B) M at positive ion mode (C) <i>SHLI</i> treatment at positive mod...
Untargeted liquid chromatography–mass spectrometry (LC-MS)-based metabolomics studies are usually ca...
Total ion current base peak intensity (BPI) chromatogram in (A) positive mode and (B) negative mode....
<p>Note: Spiking concentrations were 73 nmol/L for 8OhdG and m-Tyr, 182 nmol/L for 2-dG, o-Tyr, 3NO<...
<p><b>A</b>. Receiver Operating Characteristic curve for day-0 urinary Strong Ion Difference(SIDu) t...
List of standards used, their retention times (RT) and limits of detection (LOD) is presented in S1 ...
<p>Numbers indicate the following metabolites (quantified compounds): 1: pyruvic acid; 2: L-lactic a...
<p>Typical chromatograms of free DOX (upper panel), DOX-hyd-PEG-FA (middle panel) and DOX-ami-PEG-FA...