Expression of CTLA-4 and CCR4 in CD4⁺ T-cell subsets based on CD39 and CD25 expression.

<p>The statistical difference was deemed significant using a Mann-Whitney U test analysis if p<0.05. Horizontal bars denote median values. (A) CTLA-4 and CCR4 expression on CD4⁺ T cells from one representative uninfected donor, one HTLV-1-infected-asymptomatic carrier and one HAM/TSP patient. (B) Proportion of expression of CTLA-4 and CCR4 in CD39⁺CD25⁺ and CD39⁺CD25⁻ CD4⁺ T cells of uninfected donors, AC and HAM/TSP patients.