MiRNA expression and validation in HCV-infected Huh7.5 cells.

<p>(A) Heat map of differentially expressed miRNAs in uninfected and HCV-infected Huh7.5 cells using a continuous HCV culture system. Red indicates up-regulation of expression and green indicates down-regulation of expression. Seven miRNAs were down-regulated in HCV infection (p value <0.05). (B) Quantitative RTPCR (q-RTPCR) validation of differentially expressed miRNAs. (C) Specific fold change (FC) values in differentially expressed miRNAs in HCV infected Huh7.5 cells ranked by p-value.