ESI-MS/MS analysis of lipoprotein loaded macrophages and native LDL, oxLDL and eLDL.

<p>(A) eLDL induced significant accumulation of mono- and polyunsaturated lipid species in macrophages. oxLDL only elevated levels of monounsaturated species. (B) Lipid compositional analysis of lipoproteins. oxLDL showed substantially decreased levels of mono- and polyunsaturated lipids compared to native LDL. Saturated lipid species were decreased in eLDL, but increased in oxLDL. Mean and standard deviation of six (A) or eleven (B) replicates from different donors. Mann-Whitney <i>U</i> test: *p<0.05, **p<0.01.