<p>LNCaP cells were transfected with siANT2 or siCtrl and were incubated for 48 hr. A, ANT2 mRNA was quantified by real-time RT-PCR and normalized by GAPDH. B, Protein levels of DR5 and β-actin were analyzed by Western blotting. C, The cells were incubated with or without 50 ng/ml Apo2L/TRAIL. After 24 hr, the sub-G1 population of the cells was measured with flow cytometry. D, The cells were incubated with 20 µmol/L apigenin for 24 hr, followed by treatment with or without 50 ng/ml Apo2L/TRAIL. The Apo2L/TRAIL activity in samples without apigenin was normalized to 1. E, The cells were incubated with 20 µmol/L apigenin for 24 hr. Protein levels of DR5 and β-actin were analyzed by Western blotting. Columns, mean; bars, SD (n = 3). *<i>P</i><0...
Phytoestrogens are known to prevent tumor induction. But their molecular mechanisms of action are st...
Background: Apigenin, a common edible plant flavonoid, is a well characterised antioxidant. The adi...
[[abstract]]The molecular mechanism and possible signaling pathway of apigenin-induced cytotoxicity ...
<p>DU145 cells were transfected with siANT2 #1 or siCtrl. After 48 hr, the cells were incubated with...
<p>A, DU145 cells were treated with various concentrations of each flavonoid for 24 hr, followed by ...
<div><p>Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a pro...
<p>DU145 cells were transfected with two different ANT2 siRNAs (siANT2 #1 and #2) or a non-targeting...
Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising c...
Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising c...
<p>Apigenin binds and inhibits ANT2. Inhibition of ANT2 augments Apo2L/TRAIL sensitivity via upregul...
<p>A. Representative western blot results showed Bcl-2, Bax, caspase-3 and caspase-8 expression in t...
<p>A. The quantification of flow cytometry analyses. The flow cytometry data showed one representati...
<p>A typical DNA ladder in ANA-1 cells was observed after being treated with 50 μM apigenin for 48 h...
Apigenin is a naturally occurring plant flavonoid that possesses antioxidant, anti-cancer and anti-i...
<p>(A) HT-29 cells were transfected with siRPS9 or siCtrl. After 72 hr, the cells were treated with ...
Phytoestrogens are known to prevent tumor induction. But their molecular mechanisms of action are st...
Background: Apigenin, a common edible plant flavonoid, is a well characterised antioxidant. The adi...
[[abstract]]The molecular mechanism and possible signaling pathway of apigenin-induced cytotoxicity ...
<p>DU145 cells were transfected with siANT2 #1 or siCtrl. After 48 hr, the cells were incubated with...
<p>A, DU145 cells were treated with various concentrations of each flavonoid for 24 hr, followed by ...
<div><p>Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a pro...
<p>DU145 cells were transfected with two different ANT2 siRNAs (siANT2 #1 and #2) or a non-targeting...
Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising c...
Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising c...
<p>Apigenin binds and inhibits ANT2. Inhibition of ANT2 augments Apo2L/TRAIL sensitivity via upregul...
<p>A. Representative western blot results showed Bcl-2, Bax, caspase-3 and caspase-8 expression in t...
<p>A. The quantification of flow cytometry analyses. The flow cytometry data showed one representati...
<p>A typical DNA ladder in ANA-1 cells was observed after being treated with 50 μM apigenin for 48 h...
Apigenin is a naturally occurring plant flavonoid that possesses antioxidant, anti-cancer and anti-i...
<p>(A) HT-29 cells were transfected with siRPS9 or siCtrl. After 72 hr, the cells were treated with ...
Phytoestrogens are known to prevent tumor induction. But their molecular mechanisms of action are st...
Background: Apigenin, a common edible plant flavonoid, is a well characterised antioxidant. The adi...
[[abstract]]The molecular mechanism and possible signaling pathway of apigenin-induced cytotoxicity ...