Effects of Y27632 on haemodynamic changes in rats with endotoxaemia.

<p>Depicted are the changes of mean arterial pressure (MAP), heart rate (HR) and pressor response to NA in LPS group (lipopolysaccharide, LPS 10 mg/kg; infusion 10 min, <i>n</i> = 5) and Y27632+LPS group (Y27632 5 mg/kg followed by LPS 10 mg/kg, infusion 10 min, <i>n</i> = 5). Data are expressed as mean ± SEM.</p>*<p><i>P</i><0.05, each time-point compared to baseline in identical group;</p>#<p><i>P</i><0.05, Y27632+LPS group compared to LPS group at the same time.