Increased IL-33 in infiltrating cells in the pancreas and lung in ligation-induced acute pancreatitis.

<p>Immunohistochemistry using pancreas and lung tissue cryosections showed increased IL-33 staining of infiltrating cells 48 hrs after PD compared to sham control group in mice and rats. Small compact cells that stain intensely for IL-33 are most probably mast cells. Black arrows show IL-33 stained infiltrating cells in sham controls while red arrows show IL-33 stained infiltrating cells with increased IL-33 staining 48 hrs after PD. Brown color indicates positive IL-33 reaction. Negative controls lack primary antibody. Scale bar = 200 µm.