HCGβ increased MMP-2 activity via ERK1/2.

<p>We collected the conditional medium from the above treatment was for geltin zymography assay as the Methods. The results showed that hCGβ increased MMP-2 activity and PD98059 reduced those effects. *, indicates <i>P<0.05</i> versus control. Data were shown as means ± SEM from three separate tests. The lower panel of gel pictures showed an equal loading that a parallel SDS gel was run to test β-actin via Western blot.