The effect of estrogen and UO126 on hTERT promoter activity.

<p>Schematic diagram of hTERT promoter luciferase plasmids showing two ERE binding sites and core promoter (A). Ishikawa cells were transfected with hTERT promoter luciferase plasmids and luciferase activity was assayed after exposure to 1 uM E2 or 10 uM UO126 (U) for 36 hr. The data are presented as means ± SD of duplicated samples from at least two independent experiments. (C = control).