Knockdown of DDR2 inhibited injury and collagen deposition in rat liver.

<p>(a) Light microscopy of hematoxylin and eosin staining; arrows show the ballooning degeneration of hepatocytes; (b) immunohistochemistry of level of laminin; (c) Gordon and Sweet’s reticulin staining; (d) Masson staining of liver tissue; and (e) polarized light microscopy of Picrosirius-red staining (all 400×magnification). (f) Ratio of area of reticular fiber to total area. (g–i) Quantification analysis of immunohistochemistry results. Data are mean ± SD (n = 20). **P < 0.01.