<p>The efflux assay was performed as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055576#s2" target="_blank">Materials and Methods</a>. The values at 0 min were set as 100%. Each data point represents the mean ± SD of three independent experiments, each performed in triplicates. *<i>P<0.05</i>, versus HEK/MRP7 cells without tariquidar treatment.</p
<p>(A–C) HeLa cells were transfected with 5 nM non-targeting siRNA (A), PTPMT1 siRNA#1 (B), or PTPMT...
Background: One of the major goals of oncology is to predict the response of patients with cancer to...
<p>Tumor cells (2–3×10<sup>3</sup> cells per well) were incubated with various concentrations of pac...
<p>The accumulation of [<sup>3</sup>H]-paclitaxel was measured after preincubation in the presence o...
<p>HEK/pcDNA cells and HEK/MRP7 cells were cultured for 24 h before tariquidar was added. After 1 h ...
a<p>Values represent mean ± SD of at least three independent experiments, each performed in triplica...
<p>The percentage of the paclitaxel released was plotted as a function of time. After 1 h of incubat...
<p>Data are shown as mean ± SEM of three experiments; all experiments with one uptake assay were per...
<p>(A) The effect of 0.3 µM tariquidar treatment on the protein expression of MRP7 in HEK/pcDNA and ...
Multidrug resistance protein 7 (MRP7, ABCC10) is a recently discovered member of the ATP-binding cas...
Multidrug resistance protein 7 (MRP7, ABCC10) is a recently discovered member of the ATP-binding cas...
<p>Cells were pre-incubated with or without BBA at 2.5 µM (A) or 5 µM (B) for 2 h at 37 °C and furth...
<p>Two cell lines, HEK293-pcDNA3.1 and HEK-MRP7-2, are represented as HEK293 and MRP7, respectively....
<p>(A, B) HeLa cells were treated with 0.5 µM (A) or 1 µM (B) alexidine dihydrochloride, or a vehicl...
<p>(A) Flow cytometry was used to assess P-gp levels [as expressed by mean fluorescence intensity (M...
<p>(A–C) HeLa cells were transfected with 5 nM non-targeting siRNA (A), PTPMT1 siRNA#1 (B), or PTPMT...
Background: One of the major goals of oncology is to predict the response of patients with cancer to...
<p>Tumor cells (2–3×10<sup>3</sup> cells per well) were incubated with various concentrations of pac...
<p>The accumulation of [<sup>3</sup>H]-paclitaxel was measured after preincubation in the presence o...
<p>HEK/pcDNA cells and HEK/MRP7 cells were cultured for 24 h before tariquidar was added. After 1 h ...
a<p>Values represent mean ± SD of at least three independent experiments, each performed in triplica...
<p>The percentage of the paclitaxel released was plotted as a function of time. After 1 h of incubat...
<p>Data are shown as mean ± SEM of three experiments; all experiments with one uptake assay were per...
<p>(A) The effect of 0.3 µM tariquidar treatment on the protein expression of MRP7 in HEK/pcDNA and ...
Multidrug resistance protein 7 (MRP7, ABCC10) is a recently discovered member of the ATP-binding cas...
Multidrug resistance protein 7 (MRP7, ABCC10) is a recently discovered member of the ATP-binding cas...
<p>Cells were pre-incubated with or without BBA at 2.5 µM (A) or 5 µM (B) for 2 h at 37 °C and furth...
<p>Two cell lines, HEK293-pcDNA3.1 and HEK-MRP7-2, are represented as HEK293 and MRP7, respectively....
<p>(A, B) HeLa cells were treated with 0.5 µM (A) or 1 µM (B) alexidine dihydrochloride, or a vehicl...
<p>(A) Flow cytometry was used to assess P-gp levels [as expressed by mean fluorescence intensity (M...
<p>(A–C) HeLa cells were transfected with 5 nM non-targeting siRNA (A), PTPMT1 siRNA#1 (B), or PTPMT...
Background: One of the major goals of oncology is to predict the response of patients with cancer to...
<p>Tumor cells (2–3×10<sup>3</sup> cells per well) were incubated with various concentrations of pac...