Representative Periodic Acid Schiff (PAS)-stained photomicrographs of rat kidneys with low (≤115) and high (≥265) glomerular injury scores (GIS).

<p>A. Low magnification view of representative rat kidney section with low GIS, and (B–D) high magnification view of three representative rat kidney sections with low GIS scores demonstrate mild PAS-staining (magenta) of glomerular mesangial matrix and basement membranes, minimal PAS-staining of tubular basement membranes and tubular casts, and no glomerular sclerosis. In contrast, E, low magnification view of representative rat kidney section with high GIS, and (F–H) high magnification view of three representative rat kidney sections with high GIS show increased number of PAS-stained glomeruli with thickened mesangial matrix and basement membranes, glomerular sclerosis, tubular casts and PAS-stained thickened tubular basement membranes. Yellow <$>\raster(80%)="rg1"<$>, glomeruli, <$>\raster(80%)="rg1"<$> sclerotic glomeruli, *, tubular casts, bar = 200 micron (A, E), 50 microns (B–D, E–H).