Effects of leptin administration on body mass change (A), food intake (B) and the time spent on activity (C) in striped hamsters.

<p>Ad-PBS, hamsters that were fed <i>ad libitum</i> and treated with PBS; Ad-leptin, Ad hamsters that were treated with leptin; FR-PBS, food-restricted (FR) hamsters that were treated with PBS; FR-leptin, FR hamsters that were treated with leptin. <i>P</i>_FR **, significant effect of FR (<i>P</i><0.01); <i>P</i>_leptin *, significant effect of leptin manipulation (<i>P</i><0.05), **, <i>P</i><0.01; Different letters above the columns indicate significant differences between the groups (<i>P</i><0.05).