Normal Ca²⁺ signalling in <i>Myo5a</i>^−/− platelets.

<p>Wild-type and <i>Myo5a</i>^−/− platelets were loaded with the Ca²⁺-sensitive dye Fura-PE3. (A) Ionomycin (1 µM) was added in presence of the calcium chelator EGTA (200 µM). (B) Platelets were stimulated with the indicated concentrations of CRP in the presence of 1 mM CaCl₂. The left hand panels show representative traces (n = 3). Data in the right hand panels (mean +/− SEM, n = 3) are expressed as area under the curve (AUC).