All tested compounds concentration-dependently inhibit proliferation of endothelial cells.

<p>HMEC-1 cells were seeded to a density of 1,500 cells/well. After 24 h of incubation, a zero point control was stained with crystal violet. The remaining cells were left untreated as positive control or treated with 0.3-1-3-10–30 µM of the indicated compounds. After 72 h additional incubation, relative proliferation was determined by crystal violet staining and quantified as absorption at 550 nm.