Antibody responses in immunised mice.

<p>(<b>A</b>) Antisera were collected at 2 weeks after the 2^nd priming; (<b>B</b>) Antisera were collected at 2 weeks before rAdSS1 boosting; (<b>C</b>) Antisera were collected at 2 weeks after rAdSS1 boosting. Total IgG titres specific for the HBV antigen were determined by ELISA as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0054126#s2" target="_blank">Methods</a> section. Statistical significance was analysed and shown as <i>**p</i><0.01 and <i>*p</i><0.05. SS1: HBSS1. A, alum; C, CpG; P, poly(I:C). Adjs: control group with adjuvants mixture.