Progressive accumulation of corpora lutea.

<p>(A and B) Ovaries of <i>Tsc1^cko</i> mutant mice and control mice at the age of 6 months were sectioned serially, and hemaxytoxylin and eosin staining showed accumulation of corpora lutea in <i>Tsc1^cko</i> mutant ovaries compared with control ovaries. (C) Quantification of serial sections indicated that the numbers of corpora lutea in <i>Tsc1^cko</i> mutant ovaries were about 3 times of that in control ovaries. Bar, 250 µm. *,<i>P</i><0.05.