ELISpot analysis of IFN-γ secretion in mouse splenocytes.

<p>(A ) Splenocytes were isolated at weeks 6 after the 2nd priming; (B) Splenocytes were isolated at weeks 16 after the rAdSS1 boost. Data are expressed as spot-forming cell (SFC) responses to S and PreS1 peptide pools, and are presented as means with SEM. Significant <i>p</i> values between vaccinated groups are shown as * <i>p</i><0.05, and ** <i>p</i><0.01. SS1: HBSS1 A, alum; C, CpG; P, poly(I:C). Adjs: control group with adjuvants mixture.Data are shown as means ± SE or ± SEMs.