Example of random parameter choices producing similar output at low temperature and divergent output at high temperature.

<p>Temperature dependence fixed at: = = 1.5, = 1.6, = 3. From a chosen reference parameter point, = 0.063 µS; = 0.06 µS; = 0.1 µS, at 11°C, each maximal conductance (leak, inward and outward) is given a ±7.5% tolerance and 15 randomly generated curves are plotted across temperature. Variability in parameter space is shown in the 3D plot above. The frequency, amplitude and duty cycle of the 15 models are plotted simultaneously across the three graphs as a function of temperature.