Cortical thickness differences in adolescents with online gaming addiction compared with healthy controls.

<p>After controlling for the Beck depression inventory-II (BDI) effect, increased cortical thickness was observed in several regions in late adolescence with online gaming addiction compared to healthy controls, i.e. the left precentral cortex, precuneus, middle frontal cortex, and inferior temporal and middle temporal cortices. In addition, reduced cortical thickness in the left lateral orbitofrontal cortex (OFC), insula cortex and lingual gyrus, along with the right postcentral gyrus, entorhinal cortex, and inferior parietal cortex were detected in late adolescence with online gaming addiction.