RasGRP1 KO and RasGRP 1/3 DKO show inefficient thymocyte development beyond DN3.

Flow cytometric analysis of thymocyte development.

Kai D. Michel (344908)
Anja Uhmann (400637)
Ralf Dressel (122962)
Jens van den Brandt (70393)
Heidi Hahn (106003)
Holger M. Reichardt (344914)

April 2013

Thymocytes were isolated from Ptchflox/flox control or Ptchflox/flox</s...

Competitive chimeras demonstrate that the ATMKO defect in DN to DP development is T cell-intrinsic.

Karen S. Hathcock (218578)
Steven Bowen (405597)
Ferenc Livak (218587)
Richard J. Hodes (121071)

April 2013

This graph shows the ratio of thymocytes derived from test (ATMWT or KO CD45.2+) and c...

Transient increase of DN1 and decrease of DN2, DN3 showed in the Foxn1lacZ thymus.

Shiyun Xiao (75798)
Wen Zhang (7555)
Nancy R. Manley (358289)

February 2018

(A). Representative profiles of CD25 and CD44 on gated total CD4-CD8-</sup...

RasGRP1 KO and RasGRP1/3 DKO thymocytes display impaired proliferation of DN3 and inefficient transition from DN3E to DN3L. A.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

Intracellular TCRβ (TCRβi.c.) by forward scatter (FSC) profiles of DN3 (CD4−</sup...

RasGRP1 KO and RasGRP1/3 DKO mice display inefficient generation of DP thymocytes.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

A. Numbers of thymocytes from B6 (n = 9), 1KO (n = 6), 3KO (n = 9) and DKO (n = 13) thymi....

RasGRP1 KO, RasGRP3 KO and RasGRP1/3 DKO thymocytes show intact survival.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

Percentages of DN3 (CD4−CD8−Thy1.2+CD44−CD25+</s...

DN3 require RasGRP1 for ERK phosphorylation in response to CXCR4 activation.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

A, B. Bulk thymocytes were pre-treated with (right panels) or without (left panels) 20 µM ...

Heterogeneity of the DN4 (CD44¯ CD25¯) subset of CD4¯ CD8¯ double negative thymocytes; dependence on CD3 signaling

Falk, I.
Eichmann, K.

June 2002

Recent studies have shown that apoptotic cell death associated with selection for thymocytes that ex...

T cell development in Rasal3-deficient mice.

Ryunosuke Muro (707582)
Takeshi Nitta (55030)
Toshiyuki Okada (525877)
Hitoshi Ideta (707583)
Takeshi Tsubata (347591)
Harumi Suzuki (456196)

March 2015

(A) Flow cytometry profiles for CD4 and CD8 of thymocytes from WT and Rasal3-KO mice. (B) Proport...

DN1 and DN2 cells are preferentially increased by TSLP in FTOC and decreased in TSLPRFTOC

Qi Jiang (33521)
V McNeil Coffield (33522)
Motonari Kondo (33523)
Lishan Su (33524)

December 2011

Copyright information:Taken from "TSLP is involved in expansion of early thymocyte ...

MiR-181d over-expression reduces the number of DP thymocytes.

Serkan Belkaya (115286)
Nicolai S. C. van Oers (196487)

January 2014

(A) Total thymus cellularity in the control and miR-181d Tg mice. (B) Representative plots show C...

TNF producing SP thymocytes exhibit a lower maturation profile relative to their splenic counterparts.

Bhavana Priyadharshini (359496)
Raymond M. Welsh (170062)
Dale L. Greiner (53669)
Rachel M. Gerstein (277572)
Michael A. Brehm (264221)

February 2013

A and B, CD45.1+ P14-CD8+ thymocytes were stimulated with GP33+αCD28 for 4 ...

Effects of CD28 deficiency on γδ thymocyte proliferation, cell death and lineage commitment.

Renee M. Laird (367633)
Benjamin J. Wolf (411485)
Michael F. Princiotta (411486)
Sandra M. Hayes (367635)

May 2013

(A) Bars represent the mean ± SEM of the percentage of Ki-67+ DN TCRγδ+</s...

N3/LacZ reporter expression in DN3 thymocytes.

Sara Suliman (344384)
Joanne Tan (344385)
Keli Xu (344386)
Philaretos C. Kousis (344387)
Paul E. Kowalski (344388)
Greg Chang (344389)
Sean E. Egan (344391)
Cynthia Guidos (344393)

February 2013

(A) Lin- DN thymocytes from N3LacZ/LacZ and N3+/+ mice were loaded with FDG and stained with anti...

CHIR99021 enhances DN3b development and proliferation in the absence of Notch1 signalling.

Jan-Hendrik Schroeder (118290)
Lewis S. Bell (391988)
Michelle L. Janas (391989)
Martin Turner (391990)

March 2013

DN3b thymocytes were cultured on OP9-DL1 or OP9 cells in the presence or absence of CHIR99021 (3 ...

Flow cytometric analysis of thymocyte development.

Kai D. Michel (344908)
Anja Uhmann (400637)
Ralf Dressel (122962)
Jens van den Brandt (70393)
Heidi Hahn (106003)
Holger M. Reichardt (344914)

April 2013

Thymocytes were isolated from Ptchflox/flox control or Ptchflox/flox</s...

Competitive chimeras demonstrate that the ATMKO defect in DN to DP development is T cell-intrinsic.

Karen S. Hathcock (218578)
Steven Bowen (405597)
Ferenc Livak (218587)
Richard J. Hodes (121071)

April 2013

This graph shows the ratio of thymocytes derived from test (ATMWT or KO CD45.2+) and c...

Transient increase of DN1 and decrease of DN2, DN3 showed in the Foxn1lacZ thymus.

Shiyun Xiao (75798)
Wen Zhang (7555)
Nancy R. Manley (358289)

February 2018

(A). Representative profiles of CD25 and CD44 on gated total CD4-CD8-</sup...

RasGRP1 KO and RasGRP1/3 DKO thymocytes display impaired proliferation of DN3 and inefficient transition from DN3E to DN3L. A.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

Intracellular TCRβ (TCRβi.c.) by forward scatter (FSC) profiles of DN3 (CD4−</sup...

RasGRP1 KO and RasGRP1/3 DKO mice display inefficient generation of DP thymocytes.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

A. Numbers of thymocytes from B6 (n = 9), 1KO (n = 6), 3KO (n = 9) and DKO (n = 13) thymi....

RasGRP1 KO, RasGRP3 KO and RasGRP1/3 DKO thymocytes show intact survival.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

Percentages of DN3 (CD4−CD8−Thy1.2+CD44−CD25+</s...

DN3 require RasGRP1 for ERK phosphorylation in response to CXCR4 activation.

Dominic P. Golec (290327)
Nancy A. Dower (290328)
James C. Stone (290330)
Troy A. Baldwin (290332)

February 2013

A, B. Bulk thymocytes were pre-treated with (right panels) or without (left panels) 20 µM ...

Heterogeneity of the DN4 (CD44¯ CD25¯) subset of CD4¯ CD8¯ double negative thymocytes; dependence on CD3 signaling

Falk, I.
Eichmann, K.

June 2002

Recent studies have shown that apoptotic cell death associated with selection for thymocytes that ex...

T cell development in Rasal3-deficient mice.

Ryunosuke Muro (707582)
Takeshi Nitta (55030)
Toshiyuki Okada (525877)
Hitoshi Ideta (707583)
Takeshi Tsubata (347591)
Harumi Suzuki (456196)

March 2015

(A) Flow cytometry profiles for CD4 and CD8 of thymocytes from WT and Rasal3-KO mice. (B) Proport...

DN1 and DN2 cells are preferentially increased by TSLP in FTOC and decreased in TSLPRFTOC

Qi Jiang (33521)
V McNeil Coffield (33522)
Motonari Kondo (33523)
Lishan Su (33524)

December 2011

Copyright information:Taken from "TSLP is involved in expansion of early thymocyte ...

MiR-181d over-expression reduces the number of DP thymocytes.

Serkan Belkaya (115286)
Nicolai S. C. van Oers (196487)

January 2014

(A) Total thymus cellularity in the control and miR-181d Tg mice. (B) Representative plots show C...

TNF producing SP thymocytes exhibit a lower maturation profile relative to their splenic counterparts.

Bhavana Priyadharshini (359496)
Raymond M. Welsh (170062)
Dale L. Greiner (53669)
Rachel M. Gerstein (277572)
Michael A. Brehm (264221)

February 2013

A and B, CD45.1+ P14-CD8+ thymocytes were stimulated with GP33+αCD28 for 4 ...

Effects of CD28 deficiency on γδ thymocyte proliferation, cell death and lineage commitment.

Renee M. Laird (367633)
Benjamin J. Wolf (411485)
Michael F. Princiotta (411486)
Sandra M. Hayes (367635)

May 2013

(A) Bars represent the mean ± SEM of the percentage of Ki-67+ DN TCRγδ+</s...

N3/LacZ reporter expression in DN3 thymocytes.

Sara Suliman (344384)
Joanne Tan (344385)
Keli Xu (344386)
Philaretos C. Kousis (344387)
Paul E. Kowalski (344388)
Greg Chang (344389)
Sean E. Egan (344391)
Cynthia Guidos (344393)

February 2013

(A) Lin- DN thymocytes from N3LacZ/LacZ and N3+/+ mice were loaded with FDG and stained with anti...

CHIR99021 enhances DN3b development and proliferation in the absence of Notch1 signalling.

Jan-Hendrik Schroeder (118290)
Lewis S. Bell (391988)
Michelle L. Janas (391989)
Martin Turner (391990)

March 2013

DN3b thymocytes were cultured on OP9-DL1 or OP9 cells in the presence or absence of CHIR99021 (3 ...

Flow cytometric analysis of thymocyte development.

Kai D. Michel (344908)
Anja Uhmann (400637)
Ralf Dressel (122962)
Jens van den Brandt (70393)
Heidi Hahn (106003)
Holger M. Reichardt (344914)

April 2013

Thymocytes were isolated from Ptchflox/flox control or Ptchflox/flox</s...

Competitive chimeras demonstrate that the ATMKO defect in DN to DP development is T cell-intrinsic.

Karen S. Hathcock (218578)
Steven Bowen (405597)
Ferenc Livak (218587)
Richard J. Hodes (121071)

April 2013

This graph shows the ratio of thymocytes derived from test (ATMWT or KO CD45.2+) and c...

Transient increase of DN1 and decrease of DN2, DN3 showed in the Foxn1lacZ thymus.

Shiyun Xiao (75798)
Wen Zhang (7555)
Nancy R. Manley (358289)

February 2018

(A). Representative profiles of CD25 and CD44 on gated total CD4-CD8-</sup...

RasGRP1 KO and RasGRP 1/3 DKO show inefficient thymocyte development beyond DN3.

Abstract

Extracted data

RasGRP1 KO and RasGRP 1/3 DKO show inefficient thymocyte development beyond DN3.

Abstract

Extracted data

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