Correlation between parasitemia and total bioluminescence recorded from the entire infected animal.

<p>Male Outbred mice were injected intraperitonneally with 10²<i>Tv</i>LrDNA-luc BSF. <b>A</b>. Total light emission kinetics following D-Luciferin IP injection in a mouse with 1.10⁶ parasites/mL. The figure depicts the data from 1 out of more than 34 independent mice analyzed individually <b>B</b>. Bioluminescence over a Region of Interest (ROI) including the entire animal body surface measured 10 minutes after D-Luciferin i.p. injection. The results are expressed individually for each measurement resulting from two groups of 17 mice. Parasitemia was determined by optical microscopy concomitantly with each bioluminescence measurement. Correlation factor was calculated using Spearman's non parametric correlation test r = 0.9365, p<0.0001.