Intranasal administration of CP BPG enhances the allergen-specific IgE and total IgE Abs response.

<p>Four weeks after the initial intranasal sensitization mice were bled. Allergen-specific IgE (<b>A</b>), total IgE (<b>B</b>) levels in sera from CP-BGP or saline C57BL/6 mice were measured by ELISA. Individual serum samples were measured and expressed as the geometric means ± SEM (n = 5 per group). (<b>C</b>) Increased eosinophil influx into nasal mucosa of C57BL/6 mice sensitized intranasally with CP-BGP. Cell counts were determined by differential FACS staining of cells isolated from the nasal mucosa. Data is shown as mean ± SD (n = 5 per group). Significant differences (*** p<0.001 compared with paired control group. One representative experiment of two is shown.