Neuronal apoptosis in CA1 region of hippocampus induced by global cerebral ischemia.

<p>Detection of apoptosis in hippocampus CA1 pyramidal neurons was carried out using Tunel staing. The sham group showed a large number of neurons and almost no TUNEL-positive cells (5.1±1.2) (A). In ischemia (C) and hypothermia (B) groups, the number of neurons were decreased and substantial TUNEL-positive cells were detected. The number of TUNEL-positive cells in hypothermia group (34.4±4.2) (B) is more than in ischemia group (40.5±5.7) (C), /400×visual field.