In the absence of synaptic input, the Purkinje cell model fires spontaneously in a repeating trimodal pattern.

<p><i>A</i>, The model cell's default morphology with somatic and dendritic recording points labeled. <i>B</i>, An alternative morphology used for the model. <i>C</i>, A single trimodal repeat, recorded at the soma, with the constituent tonic (t), burst (b) and silent (s) modes labeled. <i>D</i>, The same trimodal repeat as (<i>C</i>) but recorded from a point within the dendritic tree. <i>E</i>, With no high-threshold spikes in the dendrites (<i>i</i>), firing is tonic at the soma (<i>ii</i>). With high-threshold dendritic spikes (<i>iii</i>), somatic firing has a stereotypical burst waveform (<i>iv</i>). A single dendritic spike is co-incidental with each somatic burst. The peak of the dendritic spike (<i>* in sub-panel iii</i>) causes the sudden and rapid depolarization that ends the somatic burst (<i>iv</i>). <i>F</i>, Single trimodal repeat recorded from the soma of a model variant that lacks the Kv1.2 channel. It has a markedly shorter tonic mode [t] than the standard model (<i>C</i>). <i>G</i>, The same trimodal repeat as (<i>D</i>) but recorded from a point within the model's dendritic tree. <i>H</i>, Without Kv1.2 channels, the dendritic spike frequency is higher (<i>i</i>) which results in a smaller number of spikes per somatic burst (<i>ii</i>). <i>Panels C, D, F and G are scaled by the first scale bar (40 mV, 5 s) and panels E and H by the second scale bar (40 mV, 50 ms)</i>.