<p>Cells were incubated with 0.1 μM E-3-S for 2 min at 37°C. Transport function of mutants was expressed as a percentage of the uptake measured in wild-type OATP1B1. The results represent data from three experiments, with triplicate measurements for each mutant. The results shown are means ± S.E. (<i>n = </i>3). Asterisks indicate values significantly different (<i>p</i><0.05) from that of wild-type OATP1B1.</p
The GLUT1 isoform of the mammalian passive glucose transporter family is of paramount importance in ...
AbstractThe first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene ...
<p><i>A</i>, TcdB and TcdB glucosyltransferase domain mutants (100 nM) were tested for their capacit...
<p><b>A.</b> E-3-S uptake of Asp70 mutants and <b>B</b>. Glu74 mutants. Uptake of 100 nM E-3-S was m...
<p>A. Western blot analysis for plasma membrane protein expression of double mutants. B. Transport o...
<p>Uptake of E-3-S was measure at concentrations of 5 µM, 20 µM, 50 µM and 100 µM at a 1-min interva...
<p>Transport of 100 nM E-3-S in HEK293 cells expressing OATP1B1 and its alanine-substituted mutants ...
<p>(A) COS7 cells expressing the indicated GlyT2 <i>N</i>-glycosylation mutants were biotinylated an...
<p>Transport of 100 nM or 50 µM E-3-S in HEK293 cells expressing OATP1B1 or its alanine-substituted ...
<p><b>A</b>. Uptake of OATP1B1, <b>B</b>.D70N, <b>C</b>. F73A, <b>D</b>. E74A and <b>E</b>.G76A. Upt...
<p><b>A</b>. Uptake of OATP1B1, <b>B</b>.D70N, <b>C</b>. F73Y and <b>D</b>. E74D. Uptake of E-3-S wa...
<p>Uptake of [<sup>3</sup>H] L-glutamate into HEK293 cells expressing the human EAAT3 transporter th...
<p>(A) Site directed mutation of consensus glycosylation sites in the β2 subunit alters receptor exp...
Protein glycosylation is important for nucleoside transport, and this has been demonstrated for the ...
The first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene and shar...
The GLUT1 isoform of the mammalian passive glucose transporter family is of paramount importance in ...
AbstractThe first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene ...
<p><i>A</i>, TcdB and TcdB glucosyltransferase domain mutants (100 nM) were tested for their capacit...
<p><b>A.</b> E-3-S uptake of Asp70 mutants and <b>B</b>. Glu74 mutants. Uptake of 100 nM E-3-S was m...
<p>A. Western blot analysis for plasma membrane protein expression of double mutants. B. Transport o...
<p>Uptake of E-3-S was measure at concentrations of 5 µM, 20 µM, 50 µM and 100 µM at a 1-min interva...
<p>Transport of 100 nM E-3-S in HEK293 cells expressing OATP1B1 and its alanine-substituted mutants ...
<p>(A) COS7 cells expressing the indicated GlyT2 <i>N</i>-glycosylation mutants were biotinylated an...
<p>Transport of 100 nM or 50 µM E-3-S in HEK293 cells expressing OATP1B1 or its alanine-substituted ...
<p><b>A</b>. Uptake of OATP1B1, <b>B</b>.D70N, <b>C</b>. F73A, <b>D</b>. E74A and <b>E</b>.G76A. Upt...
<p><b>A</b>. Uptake of OATP1B1, <b>B</b>.D70N, <b>C</b>. F73Y and <b>D</b>. E74D. Uptake of E-3-S wa...
<p>Uptake of [<sup>3</sup>H] L-glutamate into HEK293 cells expressing the human EAAT3 transporter th...
<p>(A) Site directed mutation of consensus glycosylation sites in the β2 subunit alters receptor exp...
Protein glycosylation is important for nucleoside transport, and this has been demonstrated for the ...
The first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene and shar...
The GLUT1 isoform of the mammalian passive glucose transporter family is of paramount importance in ...
AbstractThe first autosomal dominant missense mutation (G272A) reported within the human GLUT1 gene ...
<p><i>A</i>, TcdB and TcdB glucosyltransferase domain mutants (100 nM) were tested for their capacit...