Effect of IL-6 deficiency on collagen I expression in the kidney.

<p><b>A.</b> Representative photomicrographs of collagen I immunostaining in the kidney of WT and IL-6 KO mice after surgery (original magnification X400). <b>B.</b> Quantitative analysis of interstitial collagen I protein expression in the kidney sections of WT and IL-6 KO mice. ** <i>P</i><0.01 vs WT-control, ^#<i>P</i>>0.05 vs WT UUO, and ⁺⁺<i>P</i><0.01 vs KO UUO. n = 5 per group. <b>C.</b> Representative Western blots show the protein levels of collagen I in the kidney of WT and IL-6 KO mice. <b>D.</b> Quantitative analysis of collagen I protein expression in the kidney of WT and IL-6 KO mice. ** <i>P</i><0.01 vs WT controls, ^#<i>P</i>>0.05 vs WT UUO, and ⁺<i>P</i><0.05 vs KO UUO. n = 4 per group.