Influenza-specific mucosal IgA and IgG responses elicited by unadjuvanted and GPI-0100-adjuvanted mucosal influenza vaccine.

<p>Nose and lung wash samples from the mice described in the legend to Fig. 4 were collected on day 27 upon termination. (A) Nasal IgA responses after two immunizations. Average OD492 at each dilution ± S.E.M., n = 6 mice per group. The starting and ending dilution is 2 and 4096 respectively. (B) Lung IgA responses after two immunizations. (C) Nasal IgG responses after two immunizations. Average IgG titers ± S.E.M. Due to technical reasons only 5 samples from mice receiving unadjuvanted intrapulmonary immunization were available. (D) Lung IgG responses after two immunizations. Due to technical reasons only 5 samples from mice receiving HBS and intrapulmonary immunization were available.