<p>(A) C57BL/6 mice were infected with HKx31 and the presence of MCP-1 in the BALF was determined by ELISA at the indicated days post-infection. Data shown are means+S.E.M. from one experiment with 5 mice per time point. Similar results were found in an independent experiment at day 2 and 5 post-infection.</p
<p>(A) Viral copy number in the lungs at day 6 post-infection was determined using Q-PCR. The result...
<p>(A) TNF-α (B) IP-10 protein secreted by the mouse bone marrow derived macrophages after influenza...
(A) Mice were infected i.n. with H3N2 virus. The frequency (left panel) and absolute number (right p...
<p>(A) Neutrophil numbers in the BAL (<i>left panel</i>) and lung (<i>right panel</i>) were enumerat...
<p>A) Immunohistochemistry of influenza-infected lungs. Paraffin embedded sections of mouse lungs we...
<p>Non-asthmatic and asthmatic mice were infected i.n. with 4LD<sub>50</sub> of the CA04 virus on da...
<p>Mice were infected with 10<sup>5</sup> PFU of BJx109, HKx31 or PR8. (A) Weight loss. Mice were we...
AbstractWe explore relationships linking clinical symptoms, respiratory dysfunction, and local produ...
<p>The concentrations of chemokines and cytokines in BALF from pH1N1/OVA, pH1N1/PBS, Mock/OVA, and M...
Not infected with influenza and dark boxes denote mice infected with influenza. BALFs of the 8 mice ...
<p>DR1 and B10 mice were infected intranasally with NC or PR8 or were mock-infected with PBS. Mice w...
<p>(A) Experimental protocol of influenza-induced exacerbation of LPS/elastase exposed mice. Control...
<p>(A) Weight loss of mice inoculated with strains having different N-glycosylation sites on HA. Six...
<p>B6 mice (5 mice/group) were infected with 10<sup>5</sup> (closed triangle) or 10<sup>2</sup> (ope...
Tokine in lung were determined by real time PCR (a-c only, right). BALFs of the 8 mice in each group...
<p>(A) Viral copy number in the lungs at day 6 post-infection was determined using Q-PCR. The result...
<p>(A) TNF-α (B) IP-10 protein secreted by the mouse bone marrow derived macrophages after influenza...
(A) Mice were infected i.n. with H3N2 virus. The frequency (left panel) and absolute number (right p...
<p>(A) Neutrophil numbers in the BAL (<i>left panel</i>) and lung (<i>right panel</i>) were enumerat...
<p>A) Immunohistochemistry of influenza-infected lungs. Paraffin embedded sections of mouse lungs we...
<p>Non-asthmatic and asthmatic mice were infected i.n. with 4LD<sub>50</sub> of the CA04 virus on da...
<p>Mice were infected with 10<sup>5</sup> PFU of BJx109, HKx31 or PR8. (A) Weight loss. Mice were we...
AbstractWe explore relationships linking clinical symptoms, respiratory dysfunction, and local produ...
<p>The concentrations of chemokines and cytokines in BALF from pH1N1/OVA, pH1N1/PBS, Mock/OVA, and M...
Not infected with influenza and dark boxes denote mice infected with influenza. BALFs of the 8 mice ...
<p>DR1 and B10 mice were infected intranasally with NC or PR8 or were mock-infected with PBS. Mice w...
<p>(A) Experimental protocol of influenza-induced exacerbation of LPS/elastase exposed mice. Control...
<p>(A) Weight loss of mice inoculated with strains having different N-glycosylation sites on HA. Six...
<p>B6 mice (5 mice/group) were infected with 10<sup>5</sup> (closed triangle) or 10<sup>2</sup> (ope...
Tokine in lung were determined by real time PCR (a-c only, right). BALFs of the 8 mice in each group...
<p>(A) Viral copy number in the lungs at day 6 post-infection was determined using Q-PCR. The result...
<p>(A) TNF-α (B) IP-10 protein secreted by the mouse bone marrow derived macrophages after influenza...
(A) Mice were infected i.n. with H3N2 virus. The frequency (left panel) and absolute number (right p...