<p>Control: without any treatment. LPS, rHDLwt, rHDL74 and rHDL228 represent the groups that were treated with LPS, LPS+rHDLwt, LPS+rHDL74 and LPS+rHDL228, respectively. Compared with the LPS group, mice treated with rHDL74 showed significantly decreased levels of CRP, MCP-1 and CD14. However, mice receiving rHDL228 exhibited higher levels of these factors. In addition, compared with rHDLwt, rHDL74 significantly reduced the level of CRP and MCP-1. To confirm our experimental results, we performed three independent experiments. A: Levels of CRP. B: Levels of MCP-1. C: Levels of CD14. <sup>*</sup>P<0.05 vs. control; <sup>#</sup>P<0.05 vs. LPS; <sup>Ψ</sup>P<0.05 vs. rHDLwt. Error bars indicate the SD.</p
†Mean ±SD of the level of cytokines (pg/mg of total protein) in spleen and brains of non-treated, sa...
<p>Following LPS treatment in vivo, circulating cytokine levels of LPS-challenged mice pre-treated w...
<p>24 hours after LPS administration, the Clinical severity score was improved after CTCE-0214D plus...
<p>Mice (n = 6–9) were treated intranasally with 10 µg R-LPS (left panel), 1 µg R-LPS (middle panel)...
<p>A) Plasma isolated from HP and LP groups displayed comparable levels of CRP. Data are presented a...
<p>A. Pre-incubation with HBD does not inhibit the expression of maturation-related molecules DR (up...
<p>To investigate the effect of different rHDLs on inflammation, we examined the signaling pathway o...
<p>(A) and (B) Immunoblot for GR in sorted DCs and other immune subsets from WT and GR<sup>CD11c-cre...
(B) 12 and 18 h after CLP, WT mice received 100 μg iCpG or control ODN, and survival rates were moni...
<p>(A) There was an increase in the serum MCP-1 levels in mice early after c-lipo injection. The mic...
<p>(A) Tolerizing dose of LPS-induced loss of CD8<sup>+</sup> DCs in WT but not GR<sup>CD11c-cre</su...
<p>WT or MyD88<sup>−/−</sup> TRIF<sup>−/−</sup> mice were <i>i.p.</i> injected with LPS. <i>(A)</i> ...
<p>To study the effect of HDL on HSPC, C57BL/6 mice were infused with purified human apoA-I at 8 mg/...
<p>(A) Schematic illustration of the acute LPS-induced inflammation mouse model. (B) Compound plasma...
<p>Blood samples were collected retro-bulbar from <i>Mrp4<sup>−/−</sup></i> mice (open bars) and <i>...
†Mean ±SD of the level of cytokines (pg/mg of total protein) in spleen and brains of non-treated, sa...
<p>Following LPS treatment in vivo, circulating cytokine levels of LPS-challenged mice pre-treated w...
<p>24 hours after LPS administration, the Clinical severity score was improved after CTCE-0214D plus...
<p>Mice (n = 6–9) were treated intranasally with 10 µg R-LPS (left panel), 1 µg R-LPS (middle panel)...
<p>A) Plasma isolated from HP and LP groups displayed comparable levels of CRP. Data are presented a...
<p>A. Pre-incubation with HBD does not inhibit the expression of maturation-related molecules DR (up...
<p>To investigate the effect of different rHDLs on inflammation, we examined the signaling pathway o...
<p>(A) and (B) Immunoblot for GR in sorted DCs and other immune subsets from WT and GR<sup>CD11c-cre...
(B) 12 and 18 h after CLP, WT mice received 100 μg iCpG or control ODN, and survival rates were moni...
<p>(A) There was an increase in the serum MCP-1 levels in mice early after c-lipo injection. The mic...
<p>(A) Tolerizing dose of LPS-induced loss of CD8<sup>+</sup> DCs in WT but not GR<sup>CD11c-cre</su...
<p>WT or MyD88<sup>−/−</sup> TRIF<sup>−/−</sup> mice were <i>i.p.</i> injected with LPS. <i>(A)</i> ...
<p>To study the effect of HDL on HSPC, C57BL/6 mice were infused with purified human apoA-I at 8 mg/...
<p>(A) Schematic illustration of the acute LPS-induced inflammation mouse model. (B) Compound plasma...
<p>Blood samples were collected retro-bulbar from <i>Mrp4<sup>−/−</sup></i> mice (open bars) and <i>...
†Mean ±SD of the level of cytokines (pg/mg of total protein) in spleen and brains of non-treated, sa...
<p>Following LPS treatment in vivo, circulating cytokine levels of LPS-challenged mice pre-treated w...
<p>24 hours after LPS administration, the Clinical severity score was improved after CTCE-0214D plus...