<p>Representative contour plots showing the gate strategy used for the analysis of CD4 (middle left), CD8 (middle center), DN (middle right) γδ-T cells and the expression of CD69 (upper panels) and HLA-DR (lower panels) on DN γδ -T cells (A). Percentages of CD4<sup>+</sup> (left panels), CD8<sup>+</sup> (middle panels) and DN (right panels) γδ T-cells in healthy donors (HD, open symbols), TB (total TB, black symbols), nsTB (non-severe TB, light gray symbols) and sTB patients (severe TB, dark gray) were measured before treatment (B). The percentage of CD69 (C) and HLA-DR (D) expression within CD4<sup>+</sup> (left panels), CD8<sup>+</sup> (middle panels) and DN (right panels) γδ T-cells in HD, TB, nsTB and sTB patients were analyzed ex vivo....
<p>(A). Percentages of IFNγ-expressing CD4<sup>+</sup> CD45RO<sup>+</sup> memory T cells are shown f...
Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis (MTB)-specific ...
The immunological characterization of different cell markers has opened the possibility of consideri...
<p>Representative contour plots showing the gate strategy used for the analysis of CD4 (middle left)...
<p>Representative contour plots showing the proportions of IFN-γ producing CD4 (left panel), CD8 (mi...
<p>A–C, Strategies for determining percentages of CD27<sup>low</sup> (A), IFN-γ<sup>+</sup> (B) and ...
<p>Variation in the activation of helper and cytolytic T cells in Healthy Donors, patients with acti...
<p>PBMC were stimulated overnight using ESAT-6/CFP-10 and CD4+ and CD8+ cells were analysed by flow ...
<p>PBMC were stained with the indicated monoclonal antibodies. Panel A shows CD3 T-cells, panels B-D...
<p>Representative analyses from a patient with Tb (A) and an LTBI (B) are shown. Open red circles an...
<p><b>A.</b> Representative example of differentiation marker expression on PPD-specific CD4 T-cells...
<p>The waterfall plots show the absolute change in magnitude (SFU) between the baseline time point t...
<p>PBMC from 30 individuals with untreated active TB disease or 30 individuals with LTBI were staine...
<p>(A) Representative FACS detection of CD3<sup>+</sup>, CD4<sup>+</sup> and CD8<sup>+</sup> cells i...
<p>To investigate the contribution of B-cells to T-cell activation in the various groups of Mtb infe...
<p>(A). Percentages of IFNγ-expressing CD4<sup>+</sup> CD45RO<sup>+</sup> memory T cells are shown f...
Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis (MTB)-specific ...
The immunological characterization of different cell markers has opened the possibility of consideri...
<p>Representative contour plots showing the gate strategy used for the analysis of CD4 (middle left)...
<p>Representative contour plots showing the proportions of IFN-γ producing CD4 (left panel), CD8 (mi...
<p>A–C, Strategies for determining percentages of CD27<sup>low</sup> (A), IFN-γ<sup>+</sup> (B) and ...
<p>Variation in the activation of helper and cytolytic T cells in Healthy Donors, patients with acti...
<p>PBMC were stimulated overnight using ESAT-6/CFP-10 and CD4+ and CD8+ cells were analysed by flow ...
<p>PBMC were stained with the indicated monoclonal antibodies. Panel A shows CD3 T-cells, panels B-D...
<p>Representative analyses from a patient with Tb (A) and an LTBI (B) are shown. Open red circles an...
<p><b>A.</b> Representative example of differentiation marker expression on PPD-specific CD4 T-cells...
<p>The waterfall plots show the absolute change in magnitude (SFU) between the baseline time point t...
<p>PBMC from 30 individuals with untreated active TB disease or 30 individuals with LTBI were staine...
<p>(A) Representative FACS detection of CD3<sup>+</sup>, CD4<sup>+</sup> and CD8<sup>+</sup> cells i...
<p>To investigate the contribution of B-cells to T-cell activation in the various groups of Mtb infe...
<p>(A). Percentages of IFNγ-expressing CD4<sup>+</sup> CD45RO<sup>+</sup> memory T cells are shown f...
Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis (MTB)-specific ...
The immunological characterization of different cell markers has opened the possibility of consideri...