Effect of NPB112 on fasting plasma glucose (A) in normal C57B6 mice treated with NPB112 (n = 7 per group) and other laboratory profiles (B–E) in DIO mice before and every week after injection of vehicle or NPB112 for 6 weeks and 4 weeks of recovery (n = 24 per group).

<p>Values are expressed as mean ± SEM *, p<0.001 compared to control mice with vehicle.