Kindlin-1 and Kindlin-2 expressions during lung cancer progression.

<p><b>Kruskal-Wallis test (two sided)</b> Both of Kindlin-1 and Kindlin-2 expression are higher in NSCLC than in SCLC (<i>p</i><0.0001). Among NSCLC, Kindlin-1 expression is low in LCC, higher in AC, and the highest is seen in SCC (<i>p</i><0.0001), but Kindlin-2 has reverse expression trend: the level of Kindlin-2 is low in SCC, higher in AC and the highest in LCC (<i>p</i><0.0001). The level of Kindlin-1 expression is also correlated with the level of lung cancer differentiation: differentiated SCC and AC have higher Kindlin-1 expression than undifferentiated LCC (<i>p</i><0.0001) and High differentiated SCC has high level of Kindlin-1 expression and poorly differentiated SCC has low level of Kindlin-1 (<i>p</i> = 0.0024). This phenomenon is not obvious in AC (<i>p</i> = 0.8523). Kindlin-2 expression has no obvious relationship with the differentiation of lung cancers (<i>p</i> = 0.1759).