Deposition Patterns of Low-density Lipoprotein (LDL) in Coronary Arteries. Upper Column.

<p>Scanning of the luminal surface by CFM after administration of NB, showing (A) spotty type deposition of LDL (arrow), (B) diffuse type deposition of LDL (arrow), (C) separated co-deposition of LDL (arrow) with ApoB-100 (black arrowhead) and other lipid components that exhibited red fluorescence such as LPC, TG and ApoE-2 (white arrowhead), and (D) overlapping co-deposition of LDL (arrow) and “R” (arrowhead), respectively. Lower Column. Scanning of the transected surface by CFM after administration of NB showed (E) no deposition of LDL, but deposition of ApoB-100 in adipocytes (arrow), (F) deposition of LDL in the superficial layer of the intima (arrow), (G) deposition of LDL in the deep layer (arrow) with co-deposition of “R” in superficial layer (arrowhead), and (H) diffuse deposition of LDL in both layers (arrow). Bars = 100-µm.